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Annual TB Report 202...

According to the 2023 WHO Global TB Report, Cambodia had a TB incidence rate of 320 per 100,000 population, while the... Read More

របាយការណ៍ស្តីពីជំងឺរ...

ឆ្នាំ ២០២៣ នេះ ជាឆ្នាំទី៣នៃការអនុវត្តផែនការយុទ្ធសាស្ត្រជាតិដំណាក់កាលថ្មី ២០២១-២០៣០ ដែលមានគោលដៅបញ្ចប់ជំងឺរបេង... Read More

រូបមន្តស្តង់ដារនៃការ...

រូបមន្តស្តង់ដារនៃការព្យាបាលជំងឺរបេង នៅក្នុងកូនសៀវភៅនេះបានរៀបចំ  និងកែលំអឡើងដោយផ្អែកលើរូបមន្តណែនាំ ដោយអង្គការសុខភាពពិភពលោក... Read More

Annual TB Report 202...

In 2015, WHO reclassified the countries with a high burden of TB from 22 high TB burden countries in the previous list to 30... Read More

NATIONAL STRATEGIC P...

The National Strategic Plan (NSP) to End TB 2021-2030 sets out the directions and key initiatives that the National Centre for... Read More

Diagnosis

Molecular detection of fluoroquinolone-resistance in MDR-TB in Cambodia suggests low association with XDR phenotypes

Submitted by anyom on Sat, 10/01/2022 - 00:00
Background
Drug susceptibility testing (DST) remains an important concern for implementing treatment of MDR tuberculosis patients. Implementation of molecular tests for drug resistance identification would facilitate DST particularly in developing countries where culturing is difficult to perform. We have characterized multidrug resistant strains in Cambodia using MDTDRsl tests, drug target sequencing and phenotypic tests.
 
Methods
English

Laboratory diagnosis of tuberculosis in a large pediatric hospital in Cambodia

Submitted by anyom on Sat, 10/01/2022 - 00:00
SETTING: Tuberculosis laboratory in the Jayavarman VII Children's Hospital in Siem Reap, part of the Kantha Bopha Hospitals, the largest pediatric hospital complex in Cambodia.
 
OBJECTIVE: To determine the efficiency of on-site microscopy and rRNA amplification in children with a clinical diagnosis of tuberculosis (TB) and specimen sampling for culture.
 
English

Mediators of Innate and Adaptive Immune Responses Differentially Affect Immune Restoration Disease Associated with Mycobacterium tuberculosis in HIV Patients Beginning Antiretroviral Therapy

Submitted by anyom on Sat, 10/01/2022 - 00:00
Abstract
Background. Initiation of antiretroviral therapy (ART) in human immunodeficiency virus patients with treated or unrecognized Mycobacterium tuberculosis infection may result in tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) or ART-associated tuberculosis (ART-TB), respectively. Both conditions appear to be immune restoration disease but their immunopathogenesis is not completely understood.
 
English

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