Directly Observed Treatment, Short-course (DOTS) is a proven intervention for treatment of tuberculosis (TB), based on accurate diagnosis
and patients taking a full course of a cocktail of anti·TB drugs, which include isoniazid (INH), rifampicin (RFP), pyrazinamide (PZA), streptomicin (SM), and
ethambutol (EB). DOTS hinges on government commitment, detection, treatment, uninterrupted supply of anti-tuberculosis drugs and a monitoring
and reporting system to evaluate treatment outcomes for each patient.